Yeast Colony Group



















·  Palkova Z, Vachova L (2016) Yeast cell differentiation: Lessons from pathogenic and non-pathogenic yeasts.  Semin Cell Dev Biol. 57: 110-9.

·  Kuznetsov E, Vachova L, Palkova Z. (2016) Cellular localization of Sun4p and its interaction with proteins in the yeast birth scar.  Cell Cycle 15: 1898-907.

·  Podholova K, Plocek V, Resetarova S, Kucerova H, Hlavacek O, Vachova L, Palkova Z (2016)  Divergent branches of mitochondrial signaling regulate specific genes and the viability of specialized cell types of differentiated yeast colonies.  Oncotarget 7: 15299-314.

·  Cap M, Vachova L, Palkova Z, (2015) Longevity of U cells of differentiated yeast colonies grown on respiratory medium depends on active glycolysis.  Cell Cycle. 14: 3488-97

·  Palkova, Z, Wilkinson, D, Vachova, L (2014) Aging and differentiation in yeast populations: Elders with different properties and functions. FEMS Yeast Res 14: 96-108

·  Stovicek V, Vachova L, Begany M, Wilkinson D, Palkova Z (2014) Global changes in gene expression associated with phenotypic switching of wild yeast. BMC Genomics 15: Art. No. 136, DOI: 10.1186/1471-2164-15-136

·  Kuznetsov E, Kucerova H, Vachova L, Palkova Z (2013) SUN Family Proteins Sun4p, Uth1p and Sim1p Are Secreted from Saccharomyces cerevisiae and Produced Dependently on Oxygen Level. PLoS One 8: e73882. doi: 10.1371/journal.pone.0073882

·  Paiva S, Strachotová D, Kucerova H, Hlavacek O, Mota S, Casal M, Palkova Z, Vachova L (2013) The transport of carboxylic acids and important role of the Jen1p transporter during the development of yeast colonies. Biochem J 454: 551-558

·  Vachova, L, Hatakova, L, Cap, M, Pokorna, M, Palkova, Z (2013) Rapidly Developing Yeast Microcolonies Differentiate in a Similar Way to Aging Giant Colonies.  Oxidative Med Cell Longev, Art. No.: UNSP 102485, doi:  10.1155/2013/102485

·  Cottier, F Raymond, M, Kurzai, O, Bolstad, M, Leewattanapasuk, W, Jiménez-López, C , Lorenz, MC, Sanglard, D, Váchova, L, Pavelka, N,  Palkova, Z, Mühlschlegel, FA (2012). The bZIP transcription factor Rca1p is a central regulator of a novel CO2 sensing pathway in yeast. PLOS Pathogen 8: e1002485,   DOI: 10.1371/journal.ppat.1002485

·  Cap, M., Stepanek, L, Harant, K, Vachova,L, Palkova Z. (2012) Cell differentiation within a yeast colony: Metabolic and regulatory parallels with a tumor-affected organism. Mol Cell  46: 436-448

·  Cap, M, Vachova, L, Palkova, Z (2012) Reactive oxygen species in the signaling and adaptation of multicellular microbial communities. Oxidative Med Cell Longev, Article ID 976753, 13 pages, doi:10.1155/2012/976753

·  Palkova, Z., Vachova, L (2012) Communication and differentiation in the development of yeast colonies, In: Biocommunication in Fungi, Edited by Guenther Witzany, Springer 2012, pp 141-154

·  Pineda-Rodo, A, Vachova, L, Palkova, Z (2012) In vivo determination of organellar pH using a universal wavelength-based confocal microscopy approach, PLOS One 7: e33229. doi:10.1371/journal.pone. 0033229.

·  Strachotova, D, Holoubek, A, Kucerova, H, Benda, A, Humpolickova, J, Vachova, L, Palkova, Z (2012) Ato protein interactions in yeast plasma membrane revealed by fluorescence lifetime imaging (FLIM). BBA-Biomembranes 1818: 2126-2134 

·  Vachova, L, Cap, M., Palkova, Z. (2012) Yeast Colonies: A Model for Studies of Aging, Environmental Adaptation, and Longevity. Oxidative Med Cell Longev Art. No: 601836   DOI: 10.1155/2012/601836 

·  Vachova L, Stovicek V, Hlavacek O, Chernyavskiy O, Stepanek L, Kubinova L, Palkova Z. (2011) Flo11p, drug efflux pumps, and the extracellular matrix cooperate to form biofilm yeast colonies. J Cell Biol. 194: 679-87.  PubMed

Highlighted in “In Focus”:  Budding yeast star in their own biofilm (by B. Short)

·    Vachova L, Palkova Z (2011) Aging and longevity of yeast colony populations: metabolic adaptation and differentiation. Biochem Soc Trans. 39: 1471-5.       PubMed

·    Stovicek V, Vachova L, Kuthan M, Palkova Z. (2010) General factors important for the formation of structured biofilm-like yeast colonies. Fungal Genet Biol. 47: 1012-22, PubMed

·    Cap M, Vachova L, Palkova Z. (2010) How to survive within a yeast colony: Change metabolism or cope with stress? Commun Integr Biol 3: 198-200,  Full text

·    Vopalenska I, Stovicek V, Janderova B, Vachova L, Palkova Z (2010) Role of distinct dimorphic transitions in territory colonizing and formation of yeast colony architecture. Environ Microbiol 12: 264-77         PubMed

·    Cap M, Vachova L, Palkova Z. (2009) Yeast colony survival depends on metabolic adaptation and cell differentiation rather than on stress defense. J Biol Chem. 284: 32572-81     PubMed

·     Vachova L, Chernyavskiy O, Strachotová D, Bianchini P, Burdiková Z, Ferciková I, Kubinova L, Palkova Z (2009) Architecture of developing multicellular yeast colony: spatio-temporal expression of Ato1p ammonium exporter. Environ Microbiol. 11: 1866-1877.   PubMed

      Facultyof100  Fac100Biol

·      Palkova Z, Vachova L, Gaskova D, Kucerova H. (2009) Synchronous plasma membrane electrochemical potential oscillations during yeast colony development and aging. Mol Membr Biol. 26: 228-35.  PubMed   

·      Hlavacek O, Kucerova H, Harant K, Palková Z, Vachová L. (2009) Putative role for ABC multidrug exporters in yeast quorum sensing. FEBS Lett. 583: 1107-13.  PubMed

·      Vachova, L., Kucerova, H., Devaux,F., Ulehlova,M., Palkova,Z. (2009) Metabolic diversification of cells during the development of yeast colonies. Environ. Microbiol. 11: 494-504.  PubMed     

·      Ricicova, M., Kucerova, H, Vachova, L., Palkova, Z. (2007) Association of putative ammonium exporters Ato with detergent-resistant compartments of plasma membrane during yeast colony development: pH affects Ato1p localization in patches. BBA-Biomembranes,  1768: 1170-8,   PubMed

·      Váchová, L., Palková, Z. (2007) Caspases in yeast apoptosis-like death: Facts and artefacts. FEMS Yeast Res. 7: 12-21.    PubMed

·      Palková, Z., Váchová, L. (2006) Life within a community, benefit to yeast long-term survival. FEMS Microbiol. Rev. 30: 806-824.    PubMed

·      Vopalenska I, Hulkova M, Janderova B, Palkova Z. (2005) The morphology of Saccharomyces cerevisiae colonies is affected by cell adhesion and the budding pattern. Res Microbiol.  156: 921-31.    PubMed

·      Vachova,L., Palkova,Z. (2005) Physiological regulation of yeast cell death in multicellular colonies triggered by ammonia. J.Cell Biol.169, 711-717,    PubMed, Full text 

      Facultyof100  Fac100Biol

·      Vachova L, Devaux F, Kucerova H, Ricicova M, Jacq C, Palkova Z. (2004) Sok2p transcription factor is involved in adaptive program relevant for long-term survival of Saccharomyces cerevisiae colonies. J Biol Chem. 279: 379773-81.    PubMed , Full text

·      Palková, Z. (2004) Multicellular microorganisms: Laboratory versus nature. EMBO Rep. 5: 470-476,  review,        PubMedFull text

·      Palková, Z. , Vachova L. (2003)  Ammonia signalling in yeast colony formation. Int. Rev. Cytol. 225: 229-272,  review,   PubMedFull text

·      Kuthan,M., Devaux, F., Janderová, B., Slaninová, I, Jacq, C., Palková, Z. (2003)   Domestication of wild Saccharomyces cerevisiae is accompanied by changes in gene expression and colony morphology.  Mol. Microbiol. 47: 745-754 ,        PubMed   

·      Palkova,Z, Devaux,F., Ricicova, M, Minarikova,L., LeCrom,S., Jacq,C. (2002) Ammonia pulses and metabolic oscillations guide yeast colony development. Mol. Biol. Cell., 13: 3901-3914.                    

 PubMed, Publication web site, Full text 

·      Zikanova,B., Kuthan M, Ricicova, M, Forstova J, Palkova Z. (2002) Amino acids control ammonia pulses in yeast colonies. Biochem. Biophys. Res. Commun. 294: 962-967


·      Minarikova L, Kuthan M, Ricicova, M, Forstova J, Palkova Z. (2001) Differentiated Gene Expression in Cells within Yeast Colonies.  Exp. Cell Res. 271: 296-304.

 PubMed   WWW

·      Palková, Z. and Forstová, J. (2000). Yeast colonies synchronise their growth and development. J.Cell Sci. 113, 1923-1928.

 PubMed  Full text

·      Palková, Z., Janderová, B., Gabriel, J., Zikánová, B., Pospísek, M., Forstová, J. (1997) Ammonia mediates communication between yeast colonies, Nature 390: 532-536.

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