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New PhD position under
the programme STARS – Supporting Talented PhD Research
Students
Development of biofilm colonies
of wild yeast strains: Cell differentiation and function of different defense
mechanisms
PhD thesis will be part of the broader project of
Laboratory of Biology of Yeast Colonies focused on studies of molecular and
cellular mechanisms involved in development of yeast communities –
colonies. Previous findings revealed that Saccharomyces cerevisiae
strains isolated from natural conditions form highly structured colonies
possessing features typical of natural biofilms.
When growing on rich medium under laboratory settings, these natural strains
domesticate and start to form smooth colonies resembling colonies formed by
common S. cerevisiae laboratory strains. The subject of
PhD thesis follows recent findings (J Cell Biol. 194: 679-87, 2011) of the laboratory showing
dynamics of the development and differentiation of biofilm
colony as well as the presence of various mechanisms defending the colony
population against the environment (e.g., extracellular matrix, MDR
transporters and specific adhesins). The aim of the
project is to examine some of these processes in more detail and to determine
mechanisms of their regulation during biofilm
colony development. Specifically, the project will focus on studies of Flo
family adhesins (such as Flo11p) and regulatory
mechanisms involved in production of selectively permeable extracellular
matrix protecting cells in colony interior. Spectrum of microscopic
techniques (including confocal and electron
microscopy), molecular and cellular biology techniques (including preparation
of knockout strains and their transcriptome
analysis) and specific techniques of colony manipulation will be used during
the project.
What is STARS?
STARS is a program supporting talented PhD students at
the Faculty of Science, Charles University in Prague.
The aim of this program is to provide excellent education and an adequate
income to PhD students of the Faculty. The STARS program wants to attract the
best students from the Czech
Republic as well as from
abroad. Faculty of Science, Charles University in Prague,
is a top-quality centre of research in natural sciences.
More information and
Application form: http://www.stars-natur.cz/.
For additional information you can contact directly Zdena
Palkova (zdenap@natur.cuni.cz).
March 1, 2012 Deadline
for application
What do we offer within the STARS
program?
All PhD students receive a state-guaranteed scholarship of 6050
Czech crowns per month in their first year of study; the scholarship
increases slightly over the course of 4 years for which it is granted. In addition
to the state scholarship, the STARS program students will also be granted the
STARS-scholarship of at least 10 000 CZK per month. Their net income
will therefore be at least 16 050 CZK per month (~650 Euro). The
remuneration may be further augmented by the project supervisor. The PhD
students accepted for the STARS program will work on the selected
scientific project under the guidance of the supervisor. More
information at http://www.stars-natur.cz/.
Others
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SGD
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YEAST COMMUNITY INFO
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YEAST 2011
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XXIV.
International Conference on Yeast Genetics and Molecular Biology, Olsztyn, Poland, 11-16 July 2011
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YEAST 2009
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XXIV.
International Conference on Yeast Genetics and Molecular Biology, Manchester, UK,
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YEAST 2007
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XXIII.
International Conference on Yeast Genetics and Molecular Biology, Melbourne, Australia, July 1-6th, 2007
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YEAST 2005
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XXII. International
Conference on Yeast Genetics & Molecular Biology, August 7th -
12th, 2005, Bratislava, Slovak Republic
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YEAST 2003
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XXI th International Conference on Yeast Genetics and
Molecular Biology, August
XXX, 2003, Goetteborg,
Sweden
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YEAST 2001
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XX th International Conference on Yeast Genetics and
Molecular Biology, August 26-31, 2001, Prague, Czech
Republic
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